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Researchers Find New Substances That Break Bacterial Resistance

Scientists at the MLU (Martin Luther University Halle-Wittenberg) have designed a promising, new class of active ingredients in opposition to resistant bacteria. In original tests in insects and cell cultures, the materials were at least as effectual as normal antibiotics. The new elements aim at a special enzyme that only comes into view in bacteria in this particular form and that was not earlier the target of other antibiotics. This is the reason as to why bacteria have not yet grown any conflict to it. The team posted its work in the Antibiotics journal.

Whether the dreaded MRSA germs or staphylococcus: bacteria resistance is an issue for patients and physicians all over the world. Only a few weeks back, various huge pharmaceutical firms also declared that they were additionally slashing back their own study operation on new antibiotics.

“On the other hand, in order to be capable of treating infectious diseases in the long run and dependably, we require new active materials in opposition to which bacteria have not yet grown resistances,” claimed Professor Andreas Hilgeroth. Along with scientists from the Julius Maximilian University of Würzburg and the University of Greifswald, he is collaborating on these new active materials in a research project supported by the Federal Ministry of Education and Research.

On a related note, researchers at City of Hope might have discovered a method to sharpen the cheapest, fastest, and most precise gene editing method, CRISPR-Cas9, so that it can more productively slash out undesirable genetic data. This enhanced cutting capability might one day fast-track possible treatments for sickle cell disease, HIV, and, possibly, other immune diseases.

“Our CRISPR-Cas9 design might be the difference between testing to slash a ribeye steak using a butter knife compared to cutting it with a steak knife,” claimed Tristan Scott, lead author of the study.

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